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Figure 1 | Cell & Chromosome

Figure 1

From: Calyculin A, an enhancer of myosin, speeds up anaphase chromosome movement

Figure 1

Schematic diagram showing the relationships between myosin and its activators and inhibitors. In order for myosin to be active, its regulatory light chain (MRLC) has to be phosphorylated either by myosin light chain kinase (MLCK) or by Rho-associated kinase (Rho-K). Dephosphorylation of MRLC is done by myosin light chain phosphatase (MLCPase). Various inhibitors interfere with myosin activity: Rho-K is inhibited by Y-27632, MLCPase is inhibited by Calyculin A and myosin is inhibited by BDM.

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Cell & Chromosome

ISSN: 1475-9268