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Figure 5 | Cell & Chromosome

Figure 5

From: DNA and the chromosome – varied targets for chemotherapy

Figure 5

DNA Secondary Structures: G-Tetrad and G-quadruplex. A) Schematic illustration of G-tetrad, four guanine bases in a planar arrangement through Hoogsteen hydrogen bonds; B) G-quadruplex, parallel arrangement of four DNA strands; C) Intermolecular G-quadruplex, DNA sequences with G-rich repeats forming hairpins that dimerize to stablize bimolecular structure; and D) anti-parrallel intramolecular G-quadruplex (fold-over G-quadruplex), single DNA strand with four G-rich repeats that can fold upon themselves to form the quadruplex structure (adapted from Han and Hurley [32]).

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