Calyculin A, an enhancer of myosin, speeds up anaphase chromosome movement

Cell & Chromosome

Table 3 Effect of double treatments on anaphase chromosome movements

		# of half-bivalent pairs followed
Treatment	# of cells	total	accelerated after first drug	slowed or stopped after first drug	no change after first drug	accelerated after second drug	slowed or stopped after second drug	no change after second drug	backwards
1^st – CalA in anaphase 2^nd – Y27632 in anaphase	5	11	9	0	2	0	0	11	5
1^st – Y27632 in anaphase 2^nd – CalA in anaphase	3	7	0	7	0	7	0	0	2
1^st – CalA in anaphase 2^nd – BDM in anaphase	3	7	7	0	0	0	6	1	5*
1^st – LatB in anaphase 2^nd – CalA in anaphase	4	7	0	4	3	7	0	0	3*

* 3 of the 5 half-bivalent pairs are from cells in which the second drug (BDM) was washed out
** 2 of the 3 half-bivalent pairs are from one cell in which LatB had no effect and 1 of the 3 pairs is from a cell in which LatB slowed chromosome movement